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class="art-title">小動(dòng)物麻醉機(jī)來(lái)告訴你麻醉其實(shí)也是個(gè)技術(shù)活</h1> <div id="mtybh25oa2z" class="art-info"> 發(fā)布時(shí)間： 2019-02-21　　點(diǎn)擊次數(shù)： 1430次 </div> <div id="mtybh25oa2z" class="art-body"> 　　小動(dòng)物麻醉機(jī)來(lái)告訴你麻醉其實(shí)也是個(gè)技術(shù)活<br />　　麻醉(Anesthesia)是指用藥物或非藥物方法使機(jī)體或機(jī)體一部分暫時(shí)失去感覺(jué)，以達(dá)到無(wú)痛的目的，多用于手術(shù)或某些疾病的治療。麻醉是動(dòng)物實(shí)驗(yàn)的基本技術(shù)之一，也是保障動(dòng)物福利的一項(xiàng)重要內(nèi)容。2006年9月，我國(guó)科技部發(fā)布了《關(guān)于善待實(shí)驗(yàn)動(dòng)物的指導(dǎo)性意見(jiàn)》，規(guī)定在實(shí)驗(yàn)動(dòng)物應(yīng)用過(guò)程中，首先要控制動(dòng)物的疼痛反應(yīng)，必須使用合適劑量的麻醉劑、鎮(zhèn)痛劑或者鎮(zhèn)靜劑，否則不但有虐待動(dòng)物的嫌疑，而且會(huì)影響動(dòng)物機(jī)體的正常生理，進(jìn)而影響實(shí)驗(yàn)結(jié)果。<br />　　目前國(guó)內(nèi)用于大小鼠的麻醉藥物主要有戊巴比妥鈉、烏拉坦、水合氯醛和氯胺酮，但這些藥物存在著藥物來(lái)源受管控、安全范圍窄、麻醉深度不易控制、毒副作用強(qiáng)及個(gè)別藥物有致癌性等不足，有時(shí)將會(huì)影響正?？茖W(xué)研究的進(jìn)行。吸入麻醉具有麻醉效果好、麻醉深度易掌握、麻醉及復(fù)蘇迅速平穩(wěn)等優(yōu)點(diǎn)，在全身麻醉中占據(jù)重要地位。越來(lái)越廣泛用于實(shí)驗(yàn)室中，使用吸入麻醉藥有三個(gè)優(yōu)點(diǎn)：<br />　?。?）能通過(guò)呼吸有效地調(diào)節(jié)血中麻醉藥濃度，特別是能迅速將吸入麻醉藥從體內(nèi)“洗出”；<br />　?。?）通過(guò)測(cè)定呼氣末濃度可估計(jì)吸入麻醉藥在其作用部位(中樞神經(jīng)的系統(tǒng))的濃度；<br />　?。?）吸入麻醉可用于多種動(dòng)物的麻醉，滿(mǎn)足各種大手術(shù)的要求，在醫(yī)學(xué)界與國(guó)內(nèi)外獸醫(yī)學(xué)界得到廣泛應(yīng)用。<br />　　麻醉機(jī)的氧流量選擇<br />　　動(dòng)物的麻醉效果除了與蒸發(fā)器設(shè)置的濃度有關(guān)，也與流入動(dòng)物的氧流量有關(guān)，通過(guò)下面的列表可以看出，當(dāng)蒸發(fā)器設(shè)定濃度為2%，測(cè)量兔子的呼氣末異氟烷濃度的差異，一般流量越大，動(dòng)物呼氣末異氟烷濃度越大。<br />　　根據(jù)我們測(cè)量和經(jīng)驗(yàn)總結(jié)：一般建議小鼠氧流量為0.3-0.5L/min，大鼠為0.5-0.7 L/min.。 </div> <div id="mtybh25oa2z" class="art-next"> <dl class="shangxia"> <dd>上一篇：<a href="/Article-1752456.html">靜脈可視小鼠尾注固定器 DW-ZSQ1 裝鼠正確操作</a> </dd> <dd>下一篇：<a href="/Article-1759313.html">植保工具箱是如何做到讓植保工作事半功倍的</a> </dd> </dl> </div> </div> </div> </div> </div> </div> <div class="mtybh25oa2z" id="clear"></div>  <footer> <div id="mtybh25oa2z" class="footer"> <div id="mtybh25oa2z" class="footer1"> <div id="mtybh25oa2z" class="w1200 clearfix"> <ul class="fl footer-nav clearfix"> <li 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